research
focus areas
Comparative Biology
We are harnessing the power of nature’s diversity to uncover the mechanisms underlying longevity and disease resistance. By studying species with unique adaptations—like the cancer-resistant elephants, long-lived bowhead whales, and regenerative axolotls—we aim to decode evolutionary strategies that can be applied to human health. This comparative approach provides insights into the fundamental processes of aging and opens doors to innovative therapies.
Embryonic Rejuvenation
Our research delves into the remarkable biological reset that occurs during embryogenesis, where cells regain youthfulness and repair accumulated damage. By mapping this process and uncovering the molecular mechanisms at play, we aspire to replicate these rejuvenative effects in somatic cells, offering potential breakthroughs in reversing age-related decline.
Synthetic Biology
Leveraging cutting-edge tools from synthetic biology, we aim to redefine how aging is studied and managed. By engineering biological systems and introducing novel molecular capabilities, our goal is to develop supra-physiological interventions that go beyond conventional therapies to profoundly impact human aging.
Tooling
We are developing advanced tools for real-time aging measurement and high-resolution biological analysis. These include super-resolution imaging technologies, bioelectric profiling systems, and molecular tracking platforms that provide detailed insights into the biological processes driving aging. Our focus is on improving precision in aging research through innovative instrumentation and data acquisition systems.
Modeling
Computational modeling is a critical component of our research, enabling the simulation and prediction of aging processes. We are building virtual aging systems, computational avatars of biological aging, and machine learning models to analyze complex datasets. These models improve the predictability of therapeutic interventions and enhance the accuracy of longevity-related research, ultimately accelerating drug development and personalized aging strategies.
Dataset Accessibility and Open Science
We generate high-resolution datasets, including multi-omics data, aging clocks, and comparative biobank resources. All datasets and tools are open-access, enabling external researchers to apply these resources for modeling and hypothesis generation. Researchers can contribute to shared repositories, test models, and participate in discussions to refine methodologies and insights.
We actively foster collaboration through conferences, workshops, and networking opportunities, ensuring a global effort in advancing aging science. Researchers can provide input on tools and models, helping to refine research directions and improve data utility.
Ethics, Regulations, and Governance
We prioritize ethical considerations in embryogenesis research, synthetic biology, and cross-species experimentation. Our work complies with international regulatory standards, guided by expert oversight. Transparency is maintained through clear documentation of research policies, data use, and experimental guidelines.
